Choosing Wisely aims to promote conversations between clinicians and patients by helping patients choose care that is supported by evidence, not duplicative of other tests or procedures already received, free from harm, and truly necessary. In response to this challenge, national organizations representing medical specialists asked their providers to “choose wisely” by identifying tests or procedures commonly used in their field whose necessity should be questioned and discussed. The resulting lists of “Things Providers and Patients Should Question” are intended to spark discussion about the need—or lack thereof—for many frequently ordered tests or treatments. For providers, a suite of communication education modules was created to help them engage in these conversations with their patients. A growing library of video resources also provides diverse perspectives on the campaign’s impact and challenges.